Dr. Han's lab research currently focuses on monoamine systems (e.g. dopamine and octopamine) and investigates the molecular and cellular mechanisms crucial for distinct behavioral plasticity including learning, memory and drug addiction, and underlying neural circuits. Abnormal dopamine functions underlie ADHD, autism, schizophrenia, Parkinson’s disease and drug abuse/addiction. Han lab research contributes to better understanding of the pathogenesis mechanisms and interventions for dopamine-related disorders.
Dr. Han's lab uses molecular, immunohistochemical, pharmacological, genetic, optogeneitc, transgenic, behavioral, and statistical analyses in the fruit fly Drosphila as a model system, offering excellent multidisciplinary learning, training and education. Drosophila is a powerful model organism due to its well-characterized genetics, fully sequenced genome, and sophisticated nervous system.